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Pd (0)-CATALYZED AMINATION IN THE SYNTHESIS OF FLUORESCENT DETECTORS BASED ON 2,2'-DIAMINO-1,1'-BINAPHTHALENE (BINAM)тезисы доклада
- Авторы: Malysheva A.S., Averin A.D., Beletskaya I.P.
- Сборник: XII International Conference on Chemistry for Young Scientists "Mendeleev 2021". Book of abstracts
- Тезисы
- Год издания: 2021
- Место издания: Санкт-Петербург
- Первая страница: 583
- Аннотация: Nowadays the identification of individual enantiomers of the bio- and catalytically active compounds is of great significance for both fundamental and applied chemistry. One of the most promising approaches for the enantiomers detection is fluorescence spectroscopy due to its high selectivity and sensitivity as well as the ability to perform an express analysis. Compounds based on chiral (S)-2,2'-diamino-1,1'-binaphthalene (BINAM) were modified with oxadiamine and polyamine linkers by palladium-catalyzed amination. A series of macrocyclic compounds with exocyclic fluorophore groups such as dansyl, 7-methoxycoumarin and quinoline was obtained on their basis. Macrocycles have also been modified with additional chiral substituents [1]. Another series of compounds was obtained by Pd(0)-catalyzed amination of N,N'-di(3-bromophenyl) substituted BINAM with a number of chiral amines and decorated with various fluorophores [2]. It has been found that these compounds can be successfully used as fluorescent chemosensors for selective fluorescence detection of a number of model amino alcohols.
- Добавил в систему: Малышева Анна Сергеевна