Improvement of Ultra-Low Field Magnetic Resonance Recordings with a Multilayer Flux-Transformer-Based High-TC SQUID Magnetometerстатья
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Дата последнего поиска статьи во внешних источниках: 25 сентября 2013 г.
Авторы:
Maxim Chukharkin,
Alexey Kalabukhov,
Schneiderman Justin F.,
Fredrik Öisjöen,
Magnus Jönsson,
Minshu Xie,
Snigirev Oleg V.,
and Dag Winkler
Аннотация:We have developed a multilayer flux-transformer-based high-TC SQUID (flip-chip) magnetometer that improves signal-to-noise-ratios (SNR) in ultra-low field magnetic resonance (ulf-MR) recordings of protons in water. Direct ulf-MR-based benchmarking of the flip-chip versus a standard planar high-TC SQUID magnetometer resulted in improvement of the SNR by a factor of 2. This gain is attributable to the improved transformation coefficient (1.9 vs 5.3 nT/Φ0) that increased the signal available to the flip-chip sensor and to the lower noise at the measurement frequency (15 vs 25 fT/Hz1/2 at 4 kHz). The improved SNR can lead to better spectroscopic resolution, lower imaging times, and higher resolution in ulf-MR imaging systems based on high-TC SQUID technology. The experimental details of the sensors, calibration, and ulf-MR benchmarking are presented in this report.