Calcium activity of basolateral amygadala and CA1 field of hippocampus in mice with normal and impaired memory

Rogozhnikova, O.; Ivashkina, O.; Toropova, K.; Plusnin, V.; Solotenkov, M.; Fedotov, I.; Zheltikov, A.; Anokhin, k.

Авторы: Rogozhnikova Olga, Ivashkina Olga, Toropova Ksenia, Plusnin Victor, Solotenkov Maxim, Fedotov Ilya, Zheltikov Alexei, Anokhin konstantin
Сборник: VI Scientific School "Dynamics of Complex Networks and their Applications" (DCNA 2022)
Год издания: 2022
Первая страница: 232
Последняя страница: 235
DOI: 10.1109/DCNA56428.2022.9923061
Аннотация: Today are widely studied the processes of memory formation and impairment in humans and animals. These processes involve many structures whose activity is associated with the recognition of the new environment, objects and stimulus in it, as well as associated with the emotional state of the organism and the perceived environment. There is also known that amygdala and hippocampus are participate in the formation of associative memory [1]. In our work, we had investigated how the activity of the BLA neurons and CA1 field neurons changed in animals with normal and impaired associative memory during reconsolidation by the introduction of a protein blocker. We showed that BLA and CA1 field are active in moments of mice freezing behavior at the first acquaintance with the new environment. In associative memory retrieval, we observed an decrease in calcium activity in the CA1 field and an increase in calcium activity of BLA at freezing of mice with impaired memory. Thus, we have shown that in animals with impaired memory, there are different directions in the calcium activity changes of the neurons BLA and CA1 of the hippocampus field.
Добавил в систему: Ивашкина Ольга Игоревна

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Calcium activity of basolateral amygadala and CA1 field of hippocampus in mice with normal and impaired memoryстатья Исследовательская статья

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