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Early Effects of Cranial Irradiation by High Energy Protons on Visuomotor behavior in Nonhuman Primatesстатья
- Авторы: Tereshchenko L.V., Shamsiev I.D., Kadochnikova M.A., Krasavin E.A., Latanov A.V.
- Журнал: Biophysics
- Том: 67
- Номер: 2
- Год издания: 2022
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 257
- Последняя страница: 264
- DOI: 10.1134/S0006350922020221
- Аннотация: During long-term space missions, galactic cosmic rays lead to the risk of radiation-induced early damage to central nervous system and ensuing decline of astronaut operator activity. The visuomotor conditioned task performance was studied in three monkeys (Macaca mulatta). This task required the monkeys to execute the visually guided saccades and manual reactions. Two animals were exposed to single cranial proton irradiation (170 MeV, 3 Gy), the third animal was exposed to single proton irradiation of the parietal cortex in Bragg peak (155 MeV, 3 Gy). In course of 3 month after exposure to protons, conditioned task performance was improving in all animals. Saccade and manual responses latencies increased in 20–30 days after irradiation, remaining lengthened for the next 2 month. Parietal cortex irradiation caused greater effect on saccade and manual responses latencies. The obtained results show systemic instrumental conditioning mechanisms to be stable to proton irradiation. However, the functioning of visuomotor integration and executive control systems might be affected, resulting in increase of saccade and manual responses latencies.
- Добавил в систему: Латанов Александр Васильевич