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Importance of proliferative potential (as the ratio of a proliferative cells number and duration of mitosis) in diagnoses of malignant degree and prognosis of adrenocortical cancerстатья
Статья опубликована в журнале из списка RSCI Web of Science
Статья опубликована в журнале из перечня ВАКСтатья опубликована в журнале из списка Web of Science и/или Scopus
- Авторы: Raykhlin N.T., Bukayeva I.A., Filimonyuk A.V., Smirnova E.A., Probatova N.A., Pavlovskaya A.I., Shabanov M.A., Ponomareva M.V.
- Журнал: Архив патологии
- Том: 73
- Номер: 5
- Год издания: 2011
- Издательство: Медиа Сфера
- Местоположение издательства: М.
- Первая страница: 43
- Последняя страница: 47
- Аннотация: The aim of research has been the estimation of a proliferative potential as simultaneous detection of a proliferative cells number (Ki-67 index) and duration of mitosis (nucleolar argyrophilic protein expression - B23/nucleophosmin and C23/nucleolin) at patients with adrenocortical cancer. In according to lifetime of patients after operation 2 groups had been sorted out. The first one included patients surviving 56.12 months, the second one - 9.25 months. We\e found out that different aspects of tumor diagnosis as well distinction of benignant or malignant tumor growth, a malignant degree of tumors, a prognostic criteria of illness, survival of patients etc. must be characterized by total research both a proliferative cells fraction (Ki-67 index) and a rate of mitosis (expressions of B23/nucleophosmin and C23/nucleolin).
- Добавил в систему: Пономарева Мария Владимировна