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Evaluation of plant-based UV filters potential in modernconcept view of skin photoprotectionстатья
- Авторы: Nemyatykh O.D., Terninko I.I., Sabitov A.S., Lyashko A.I., Sakipova Z.B.
- Журнал: Фармация и фармакология
- Номер: 10(4)
- Год издания: 2022
- Издательство: Пятигорский медико-фармацевтический институт - филиал ФГБОУ ВО ВолгГМУ Минздрава России
- Местоположение издательства: Пятигорск
- Первая страница: 308
- Последняя страница: 319
- DOI: 10.19163/2307-9266-2022-10-4-308-319
- Аннотация: A therapeutic plants potential is based on the pharmacological effects due to their phytochemical profile. Today, scientificinterest in botanicals is increasing as a result of recent research that looks at the prospect of using these raw materials for thecosmetic industry as a means to protect the skin from the harmful effects of UV rays.The aim of the study was to evaluate a potential of plant-based UV-filters in modern concept view of skin photoprotection.Materials and methods. A systematic literature search was carried out using the electronic information arrays PubMed,Scopus, Google Scholar, eLibrary. The search depth was 10 years (the period from 2010 to 2021). The search was carried outby the following keywords: antioxidants, cosmetics, photoprotection, chemical composition, pharmacological action.Results. In the paper, modern principles of skin photoprotection based on the use of chemical or physical UV-filters areconsidered and scientifically substantiated A trend for the use of plant-based materials and their components in theformulation of photoprotectors was notified. That is associated with a wide activity spectrum, the absence of a xenobioticeffect, and a high bioavailability of organic plant compounds.Conclusion. The data analysis from scientific publications demonstrated a potential photoprotective activity of plant-basedbiologically active substances due to antioxidant, anti-inflammatory and anti-radical effects. The results of the study are atheoretical basis for a further comprehensive experimental study of plant objects in order to obtain a pool of evidence in thefield of photoprotection in in vivo experiments.Keywords: plant-based UV filters; photoprotection; concept of modern skin photoprotectionAbbreviations: IPD – Immediate Pigment Darkening; IPF – Immune Protection Factor; NADH – nicotinamide adeninedinucleotide; NADPH – nicotinamide adenine dinucleotide phosphate; PPD – Persistent Pigment Darkening; SPF – SunProtection Factor; UVA – ultraviolet A rays; UVB – ultraviolet B rays; UVC – ultraviolet C rays; ROS – reactive oxygen species;BASs – biologically active substances; WHO – World Health Organization; DNA – deoxyribonucleic acid; UV rays – ultravioletrays.
- Добавил в систему: Немятых Оксана Дмитриевна