Bioinspired Electropun Fibrous Materials Based on Poly-3-Hydroxybutyrate and Hemin: Preparation, Physicochemical Properties, and Weathering

Tyubaeva, P.M.; Varyan, I.A.; Zykova, A.K.; Yarysheva, A.Y.; Ivchenko, P.V.; Olkhov, A.A.; Arzhakova, O.V.

Авторы: Tyubaeva P.M., Varyan I.A., Zykova A.K., Yarysheva A.Yu, Ivchenko P.V., Olkhov A.A., Arzhakova O.V.
Журнал: Polymers
Том: 14
Год издания: 2022
Издательство: MDPI
Местоположение издательства: Basel, Switzerland
Первая страница: 4878
DOI: 10.3390/polym14224878
Аннотация: The development of innovative fibrous materials with valuable multifunctional propertiesbased on biodegradable polymers and modifying additives presents a challenging direction for modernmaterials science and environmental safety. In this work, high-performance composite fibrousmaterials based on semicrystalline biodegradable poly-3-hydroxybutyrate (PHB) and natural ironcontainingporphyrin, hemin (Hmi) were prepared by electrospinning. The addition of Hmi to the feedPHB mixture (at concentrations above 3 wt.%) is shown to facilitate the electrospinning process andimprove the quality of the electrospun PHB/Hmi materials: the fibers become uniform, their averagediameter decreases down to 1.77 m, and porosity increases to 94%. Structural morphology, phasecomposition, and physicochemical properties of the Hmi/PHB fibrous materials were studied bydiverse physicochemical methods, including electronic paramagnetic resonance, optical microscopy,scanning electron microscopy, and energy-dispersive X-ray spectroscopy, elemental analysis, differentialscanning calorimetry, Fourier-transformed infrared spectroscopy, mechanical analysis, etc.The proposed nonwoven Hmi/PHB composites with high porosity, good mechanical properties, andretarded biodegradation due to high antibacterial potential can be used as high-performance androbust materials for biomedical applications, including breathable materials for wound disinfectionand accelerated healing, scaffolds for regenerative medicine and tissue engineering.
Добавил в систему: Аржакова Ольга Владимировна

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Bioinspired Electropun Fibrous Materials Based on Poly-3-Hydroxybutyrate and Hemin: Preparation, Physicochemical Properties, and Weatheringстатья

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