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Multilayered Organic Semiconductors for High Performance Optoelectronic Stimulation of Cellsстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Markov A., Gerasimenko A., Boromangnaeva A-K, Shashova S., Iusupovskaia E., Kurilova U., Nikitina V., Suetina I., Mezentseva M., Savelyev M., Timashev P., Telyshev D., Liang X-J
- Журнал: Nano Research
- Год издания: 2022
- Издательство: Tsinghua Univ Press
- Местоположение издательства: China
- DOI: 10.1007/s12274-022-5130-8
- Аннотация: The efficiency of devices for bioelectronic applications, including cell and tissue stimulation, is heavily dependent on the scaleandtheperformance level. With miniaturization of stimulation electrodes, achieving a sufficiently high current pulse to elicit action potentialsbecomesan issue. Herein we report on our approach of vertically stacking organic p-n junctions to create highly-efficient multilayeredorganicsemiconductor (MOS) photostimulation device. A tandem arrangement substantially increases the photovoltage and charge densitywithoutsacrificing lateral area, while not exceeding 200-500 nm of thickness. These devices generate four-times higher voltages and at least doublethe charge densities over single p-n junction devices, which allows using lower light intensities for stimulation. MOS devicesshowanoutstanding stability in the electrolyte that is extremely important for forthcoming in vivo experiments. Finally, we have validated MOSdevicesperformance by photostimulating fibroblasts and neuroblasts. and finding that using tandem devices leads to more effective actionpotentialgeneration. As a result, we obtained up to 4 times enhanced effect in cell growth density using 3 p-n layered devices. Theseresultscorroborate the conclusion that MOS technology not only can achieve parity with state-of-the-art silicon devices, but can exceedtheminminiaturization and performance for biomedical applications.https://www.sciopen.com/article/pdf/10.1007/s12274-022-5130-8.pdf
- Добавил в систему: Никитина Вита Николаевна