|
ИСТИНА |
Войти в систему Регистрация |
ИПМех РАН |
||
Reaction of glyoxal with nucleic acid components. IV. Reduction of guanine-glyoxal adduct with sodium borohydrideстатья
- Авторы: Mazurenko NN, Broude NE, Budowsky EI
- Журнал: Biochimica et Biophysica Acta - General Subjects
- Том: 254
- Номер: 3
- Год издания: 1971
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Первая страница: 389
- Последняя страница: 392
- DOI: 10.1016/0005-2787(71)90869-0
- Аннотация: An attempt to stabilize guanine-glyoxal adduct by NaBH4 reduction was made. The reaction product was found to be 2-β-hydroxyethylamino-6-oxopurine, which proved stable under various conditions. The experimental conditions used for monomer reduction (pH 12.7, 30°, 2 h) can be applied for analysis of polymers. A label can be introduced into a modified guanine nucleus by means of NaB3H4.
- Добавил в систему: Мазуренко Наталья Николаевна