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Inter- and intra-observer variability of computed tomography-based parenchymal- and ductal diameters in chronic pancreatitis: a multi-observer international studyстатья
- Авторы: Borgbjerg Jens, Steinkohl Emily, Olesen Søren S., Akisik Fatih, Bethke Anne, Bieliuniene Edita, Christensen Heidi S., Engjom Trond, Haldorsen Ingfrid S., Kartalis Nikolaos, Lisitskaya Maria V., Naujokaite Gintare, Novovic Srdan, Ozola-Zālīte Imanta, Phillips Anna E., Swensson Jordan K., Drewes Asbjørn M., Frøkjær Jens B.
- Журнал: ABDOMINAL RADIOLOGY
- Год издания: 2022
- DOI: 10.1007/s00261-022-03667-2
- Аннотация: Abstract Purpose: The need for incorporation of quantitative imaging biomarkers of pancreatic parenchymal and ductal structures has been highlighted in recent proposals for new scoring systems in chronic pancreatitis (CP). To quantify inter- and intra-observer variability in CT-based measurements of ductal- and gland diameters in CP patients. Materials and methods: Prospectively acquired pancreatic CT examinations from 50 CP patients were reviewed by 12 radiologists and four pancreatologists from 10 institutions. Assessment entailed measuring maximum diameter in the axial plane of four structures: (1) pancreatic head (PDhead), (2) pancreatic body (PDbody), (3) main pancreatic duct in the pancreatic head (MPDhead), and (4) body (MPDbody). Agreement was assessed by the 95% limits of agreement with the mean (LOAM), representing how much a single measurement for a specific subject may plausibly deviate from the mean of all measurements on the specific subject. Bland-Altman limits of agreement (LoA) were generated for intra-observer pairs. Results: The 16 observers completed 6400 caliper placements comprising a first and second measurement session. The widest inter-observer LOAM was seen with PDhead (± 9.1 mm), followed by PDbody (± 5.1 mm), MPDhead (± 3.2 mm), and MPDbody (± 2.6 mm), whereas the mean intra-observer LoA width was ± 7.3, ± 5.1, ± 3.7, and ± 2.4 mm, respectively. Conclusion: Substantial intra- and inter-observer variability was observed in pancreatic two-point measurements. This was especially pronounced for parenchymal and duct diameters of the pancreatic head. These findings challenge the implementation of two-point measurements as the foundation for quantitative imaging scoring systems in CP. Keywords: Chronic pancreatitis; Computed tomography; Observer agreement.
- Добавил в систему: Лисицкая Мария Валерьевна