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Novel analytical approaches to determination of chemical warfare agents and related compounds for verification of nonproliferation of chemical weaponsстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 17 октября 2017 г.
- Авторы: Rybalchenko Igor, Rodin Igor, Baygildiev Timur, Stavrianidi Andrey, Braun Arcady, Morozik Yury, Shpigun Oleg
- Журнал: Pure and Applied Chemistry
- Том: 89
- Номер: 10
- Год издания: 2017
- Издательство: International Union of Pure and Applied Chemistry
- Местоположение издательства: United States
- Первая страница: 1491
- Последняя страница: 1505
- DOI: 10.1515/pac-2016-1208
- Аннотация: In this paper a summary of the author’s approaches for investigation of the mass spectral behavior of some chemical warfare agents (CWAs), their degradation products and metabolites, as well as the results of development of analytical methods for confirmation of nerve and blister agents application are presented. Hydrolysis and oxidation metabolites of nerve agents, sulfur mustard and lewisite were used as biomarkers of the exposure. Sensitive analytical methods have been developed for their detection, based mainly on tandem mass spectrometry coupled with liquid chromatography. Several techniques for fast screening of CWAs degradation products based on capillary electrophoresis were also proposed. Some of developed approaches were successfully applied in the frame of the proficiency testing system of the Organization for the Prohibition of Chemical Weapons
- Добавил в систему: Родин Игорь Александрович