Arabidopsis DNA topoisomerase I alpha is required for adaptive response to light and flower developmentстатья
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Дата последнего поиска статьи во внешних источниках: 8 августа 2017 г.
Аннотация:DNA topoisomerase I alpha (TOP1α) plays a specific role in
Arabidopsis thaliana development and is required for stem cell
regulation in shoot and floral meristems. Recently, a new role
independent of meristem functioning has been described for TOP1α,
namely flowering time regulation. The same feature had been
detected by us earlier for fas5, a mutant allele of TOP1α. In this
study we clarify the effects of fas5 on bolting initiation and analyze the
molecular basis of its role on flowering time regulation. We show that
fas5 mutation leads to a constitutive shade avoidance syndrome,
accompanied by leaf hyponasty, petiole elongation, lighter leaf color
and early bolting. Other alleles of TOP1α demonstrate the same
shade avoidance response. RNA sequencing confirmed the
activation of shade avoidance gene pathways in fas5 mutant plants.
It also revealed the repression of many genes controlling floral
meristem identity and organ morphogenesis. Our research further
expands the knowledge of TOP1α function in plant development and
reveals that besides stem cell maintenance TOP1α plays an
important new role in regulating the adaptive plant response to light
stimulus and flower development.