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Adaptive changes of the antioxidant system in oncogynecological patients with additional therapyтезисы доклада
- Авторы: Goroshinskaya I.A., Menshenina A.P., Popova N.N., Kachesova P.S., Tumanyan S.V., Frantsiyants E.M., Kaplieva I.V., Shikhlyarova A.I., Verenikina E.V., Nemashkalova L.A.
- Сборник: Journal of Clinical Physiology and Pathology (JCPP)
- Том: 2
- Тезисы
- Год издания: 2023
- Издательство: РУДН
- Местоположение издательства: М.
- Первая страница: 25
- Последняя страница: 28
- Аннотация: The intensification of free radical oxidation plays an important role in the mechanisms of development of many diseases, including malignant growth. Reactive oxygen species are considered, on the one hand, as carcinogenesis initiators and the most important factors in cancer progression [1,2,3], on the other hand, as agents that promote the elimination of cancer cells in cancer therapy [4]. More intensive peroxidation of lipids (LPO) and proteins, accompanied by a violation of antioxidant protection, was demonstrated in the progression of various cancers [1,4,5], including studies on gynecological cancers conducted at the National Medical Research Centre for Oncology: ovarian cancer (OC) depending on its prevalence and severity [6]; cervical cancer (CC) [7,8]; vulvar cancer [9]. An abnormal antioxidant status is associated with the development of oxidative stress [10].
- Добавил в систему: Каплиева Ирина Викторовна