Characteristics of the use of scanning capillary microscopy in biomedical research

Sovetnikov, T.O.; Akhmetova, A.I.; Maksimova, N.E.; Terent’ev, A.D.; Evtushenko, G.S.; Rybakov, Y.L.; Gukasov, V.M.; Yaminskii, I.V.

Авторы: Sovetnikov T.O., Akhmetova A.I., Maksimova N.E., Terent’ev A.D., Evtushenko G.S., Rybakov Yu L., Gukasov V.M., Yaminskii I.V.
Журнал: Bio-Medical Engineering
Том: 57
Номер: 4
Год издания: 2023
Издательство: Springer Nature
Местоположение издательства: Switzerland
Первая страница: 250
Последняя страница: 253
DOI: 10.1007/s10527-023-10309-4
Аннотация: Advances in scanning capillary microscopy (SCM) in studies of living objects have generated interest in this technique: over its 30 years of existence, more than 300 articles and numerous reviews describing the development of SCM have been published. The growth of dendrites and axons and the dynamics of actin in living cells have been visualized, changes in the volumes of nerve cells during migration have been measured, changes in the structure of the cell membrane during endocytosis of nanoparticles have been studied, the topography and stiffness of living fibroblasts have been assessed, and more. The uniqueness of the method lies not only in its provision of contactless three-dimensional visualization of living cells in their natural environment with nanometer spatial resolution, but also in the opportunity of using capillaries as sensors for reactive oxygen species, various neurotransmitters, and growth factors, as well as for assessing concentrations, etc., which opens up opportunities for addressing a variety of tasks in biomedicine.
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Characteristics of the use of scanning capillary microscopy in biomedical researchстатья

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