Аннотация:Silicon nanoparticles (SiNPs) are successfully used in various biomedical applications due to their low toxicity and biodegradability. In this paper we study the possibility of employment of laser-ablated SiNPs in biophotonics. The particles are formed by femtosecond and picosecond laser ablation of monocrystalline and porous silicon targets in various liquids: water, ethanol, liquid nitrogen, and aqueous ethanol solution with silver nitrate. In the latter case, it is possible to decorate the SiNPs surface with silver nanoparticles (Si/Ag).