Аннотация:A total data row of monthly average and mean annual air temperature values T in Moscow was studied for the entire period of regular instrumental measurements, since 1779. On average, over the last 243 years, T in Moscow increased by 0.012 ˚C/year. The warming at the end of the Little Ice Age gave way to a slight cooling in the middle and end of the 19th century and, then, a current new warming since the beginning of the 20th century, and its slight deceleration in recent decades. Statistically significant and strongest warming is detected in winter and spring; in summer and early autumn, centennial changes in T are insignificant. The distribution functions of T in summer are close to the Normal law, in winter they have strong negative asymmetry. At the end of the 18th century extremely low minimal air temperature in Moscow was observed up to –37÷–39˚С. The mean-annual T increased on 2.8 ˚С at the urban periphery of the city and at least on 1.6 ˚С at rural zone of Moscow region on aver-age for the period 1780–2022. The degree of Moscow climate continentality since 1780s in general decreased.