Antimicrobial Chitosan/Hyaluronic Acid/Genipin/Nano Silver Sponges Obtained in Solutions of Carbonic Acid: a Study of Structure and Properties

Авторы: Chaschin I.S., Dreger E.I., Ivanova N.M., Vasiliev V.G., Anuchina N.M., Perepelkin E.I., Kildeeva N.R.
Журнал: ИНЭОС OPEN
Год издания: 2024
Издательство: Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А. Н. Несмеянова Российской академии наук
Местоположение издательства: Москва
DOI: 10.32931/io2330a
Аннотация: The aim of this work was to develop an antimicrobial sponge composed of chitosan, hyaluronic acid, and nano silver particles (AgNPs), which are used in biomedical applications as a hemostatic material for the treatment of wounds infected by drug-resistant bacteria. The sponges were obtained using an approach based on the preparation of polymer solutions in a biocompatible and self-neutralizing solvent, namely, carbonic acid. The resulting sponges were characterized by SEM and FTIR spectroscopy. It was found that the resulting sponges have good water absorption, mechanical properties, and strength. They also show pronounced activity against E. coli and S. aureus.
Добавил в систему: Перепелкин Евгений Игоревич

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