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The effect of nitric oxide (II) on leukotrienes synthesis and apoptosis in human phagocyting neutrophilsстатья
- Авторы: Viryasova G.M., Golenkina E.A., Sud’ina G.F.
- Журнал: Russian journal of immunology : RJI : official journal of Russian Society of Immunology
- Том: 10
- Номер: 2
- Год издания: 2016
- Издательство: The Journal
- Местоположение издательства: Moscow, Russia (Federation)
- Первая страница: 67
- Последняя страница: 69
- Аннотация: The effect of nitric oxide (II) on apoptosis of human neutrophils and the synthesis of leukotrienes in vitro in phagocyting neutrophils was investigated. Particles of opsonized zymosan were used as phagocytosis object. It is assumed that NO affects the zymosan induced apoptosis and arachidonic acid cascade, shifting it towards the formation of 5-oxo-ETE, and this plays an important role in the apoptosis of phagocyting neutrophils.
- Добавил в систему: Вирясова Галина Михайловна