Sensor platform for noninvasive evaluation of pulmonary oxidative statusстатья
Статья опубликована в высокорейтинговом журнале
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Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 5 марта 2025 г.
Аннотация:We report on sensor platform including both the advanced nanostructured Prussian Blue based hydrogen peroxide sensor and the cooling-free breath aerosol (BA) condenser. The latter provides an order of magnitude more concentrated BA samples as compared to breath condensate collected traditionally through cooling; the conclusion is based on both: specimen's conductivity, the generally accepted dilution marker, and the evaluated H2O2 levels (2.2–3.2 μM for healthy subjects). Reliable detection of submicromolar H2O2 content is possible with the sensor based on nanostructured Prussian Blue (0.45-0.70 nmol cm−2) stabilized with nickel hexacyanoferrate (1.0-1.3 nmol cm−2). A possibility to discover the noninvasively accessed marker for post-COVID-19 syndrome illustrates the horizons of the platform in clinical diagnostics.