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Rationale, implementation considerations, delineation and planning target objective recommendations for volumetric modulated arc therapy and helical tomotherapy TBI, TMI, TMLI and TLIстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Hoeben Bianca A.W., Saldi Simonetta, Aristei Cynthia, Engellau Jacob, Ocanto Abrahams, Hiniker Susan M., Misson-Yates Sarah, Kobyzeva Daria A., Pazos Montserrat, George Mikhaeel N., Rodriguez-Roldan Marta, Seravalli Enrica, Bosman Mirjam E., Han Chunhui, Losert Christoph, Engström Per E., Fulcheri Christian P.L., Zucchetti Claudio, Ferrer Carlos, Hussein Mohammad, Loginova Anna A., Clark Catharine H., Wong Jeffrey Y.C.
- Журнал: Radiotherapy and Oncology
- Том: 206
- Год издания: 2025
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Номер статьи: 110822
- DOI: 10.1016/j.radonc.2025.110822
- Аннотация: As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their TBI setup to a conformal isocentric technique, providing superior homogeneity and control of the target prescription dose, and more freedom for individualized organ-at-risk sparing or dose-escalation. Also, more specifically bone-marrow- and/or lymphatics-targeted therapies such as Total Marrow (+ Lymphoid) Irradiation (TMI / TMLI), and Total Lymphoid Irradiation (TLI) are established and prospectively evaluated in several centers. With each center developing their own methods, a new practice heterogeneity is arising, as was the case for decades with conventional TBI. To provide a ground base – and therefore more options for more homogeneous and comparable practice − for centers who are implementing conformal isocentric techniques, a group of early adopters of isocentric conformal TBI and TM(L)I came together to convey issues they encountered during clinical implementation, and form consensus recommendations for delineation and planning targets, based on available literature evaluation and shared experience. These recommendations follow previously published recommendations regarding technical setup of conformal isocentric TBI / TM(L)I techniques.
- Добавил в систему: Логинова Анна Анзоровна