|
ИСТИНА |
Войти в систему Регистрация |
ИПМех РАН |
||
Efficient Synthesis of Core-Fluorinated BODIPY-3,5-Diamidesстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Shambalova Victoria E., Mikheeva Sofiya R., Aldoshin Alexander S., Moiseeva Anna A., Safonova Evgeniya A., Gorbunova Yulia G., Nenajdenko Valentine G.
- Журнал: International Journal of Molecular Sciences
- Том: 26
- Номер: 10
- Год издания: 2025
- Издательство: MDPI
- Местоположение издательства: Basel, Switzerland
- Номер статьи: 4484
- DOI: 10.3390/ijms26104484
- Аннотация: A modular synthesis of a new family of core-fluorinated BODIPYs was elaborated. β-Fluoro-β-nitrostyrenes were used as starting materials to prepare a set of mono-fluorinated pyrrole-2-amides using the Barton-Zard reaction with 2-isocyanoacetamides. The prepared monofluorinated building blocks were successively transformed into the corresponding dipyrromethanes and 1,7-difluoro-BODIPY-3,5-diamides. As a result, a new family of luminophores with a combination of fluorescence and photosensitizing properties was obtained. The photophysical properties of novel BODIPYs were studied by UV-vis and fluorescence spectroscopy, cyclic voltammetry and DFT calculations. In addition, their ability to generate singlet oxygen was assessed. The properties of 1,7-difluoro-BODIPY-3,5-diamides were compared with their analogues to reveal the substituent effect at the 3,5-positions. The fluorescent properties of the obtained dyes were significantly improved in comparison to their 3,5-diester analogous.
- Добавил в систему: Алдошин Александр Сергеевич
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Заключение-IJMS-2025.jpeg | Заключение-IJMS-2025.jpeg | 736,5 КБ | 12 мая 2025 [alexander.aldoshin] | |
| 2. | Полный текст | ijms-26-04484.pdf | 8,5 МБ | 11 мая 2025 [alexander.aldoshin] |