Identification of genetic changes acquired by replicate lineages of Podospora anserina during long-term submerged cultivation

Авторы: Сафина К.Р., Вахрушева О.А., Базыкин Г.А., Мажейка И.С., Буданова Е.В., Камзолкина О.В., Кудрявцева О.А., Кондрашов А.С.
Сборник: Сборник докладов 41-ой Междисциплинарной школы-конференции "Информационные технологии и системы" - ИТиС 2017
Тезисы
Год издания: 2017
Аннотация: Ascomycete fungus Podospora anserina is frequently used as a model organism in studies on the mechanisms of ageing due to its limited lifespan with clear signs of senescence on solid media. However, it shows no evidence of senescence when cultured under aeration in liquid media. The mechanisms underlying the unlimited vegetative growth are unknown. We conducted a long-term submerged cultivation experiment of eight replicate lineages of P. anserina and analyzed genetic changes that arose and became fixed in these lineages during the cultivation. Several lines of evidence suggest that some of the acquired mutations might be adaptive.
Добавил в систему: Кудрявцева Ольга Александровна

	ИСТИНА	Войти в систему Регистрация
	ИПМех РАН
	Главная Поиск Статистика О проекте Помощь

ИСТИНА