Место издания:Saint-Peterburg, Solo puplishing Saint-Peterburg Russia
Первая страница:114
Последняя страница:114
Аннотация:Current strategy of structure elucidation for nitrogen containing aromatic heterocycles imply routine use of 15N HMBC experiments optimized on certain values of long-range spin-spin couplings 15N-H. To our knowledge, the proper choice of reliable supporting data for these parameters is difficult. There is little or no experimental data available up to date even for such important model systems like indole, quinoline and azobenzene - the basic structures for alkaloids, variety of natural products and dye-stuffs.Accurate data for isotope chemical shifts of 1H and 13C nuclei caused by substitution of 14N by 15N in aromatic compounds is collected. Analysis of these data reveals systematic trends, which can be of use for practical applications.