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Physiological basis of the pathogenesis of alcohol-induced skeletal muscle injuryстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 5 августа 2018 г.
- Авторы: Zinovyeva O.E., Emelyanova A.Yu, Samkhaeva N.D., Shcheglova N.S., Shenkman B.S., Nemirovskaya
- Журнал: Human Physiology
- Том: 42
- Номер: 3
- Год издания: 2016
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 343
- Последняя страница: 349
- DOI: 10.1134/S0362119716020171
- Аннотация: Alcohol-induced muscle damage (AIMD) is an umbrella term that includes all forms of alcoholic myopathy developing in acute or chronic alcohol intoxication. The most common form of destruction of skeletal muscles in alcoholism is chronic alcoholic myopathy, which develops independently of other alcohol-induced disorders, such as polyneuropathy, the malabsorption syndrome, and liver damage, but may be combined with them. The atrophy of muscle fibers underlies skeletal muscle destruction in chronic AIMD. Type II muscle fibers are affected to a greater degree than type I muscle fibers. To date, the pathogenesis of chronic alcoholic myopathy has been studied insufficiently. The imbalance between protein synthesis and proteolysis, as well as increased apoptosis rate, is discussed.
- Добавил в систему: Немировская Татьяна Леонидовна