Interrelation of Blood Microrheological Parameters Measured by Optical Methods and Whole Blood Viscosity in Patients Suffering from Blood Disorders: a Pilot Study

Ermolinskiy, P.B.; Lugovtsov, A.E.; Maksimov, M.K.; Umerenkov, D.A.; Moldon, P.A.; Sveshnikova, A.N.; Pshonkin, A.V.; Smetanina, N.S.; Priezzhev, A.V.

Авторы: Ermolinskiy Petr B., Lugovtsov Andrei E., Maksimov Matvei K., Umerenkov Danila A., Moldon Pavel A., Sveshnikova Anastasia N., Pshonkin Alexey V., Smetanina Natalia S., Priezzhev Alexander V.
Журнал: Journal of Biomedical Photonics & Engineering
Том: 10
Номер: 2
Год издания: 2024
Издательство: Samara National Research University
Местоположение издательства: Samara
Первая страница: 020306-1
Последняя страница: 020306-9
Номер статьи: 020306
DOI: 10.18287/jbpe24.10.020306
Аннотация: The perfusion of tissues and blood flux strongly depend on several interdependent parameters, such as viscosity of blood, red blood cell aggregation and red blood cell deformation. In case of many blood disorders these parameters are altered. This pilot study aimed to investigate the relationship between whole blood viscosity and microrheological parameters in patients with essential thrombocythemia (ET), as well as to compare microrheological parameters in patients with ET, erythrocytosis and spherocytosis. Blood viscosity measurements were performed using a rotational viscometer, while microrheological parameters were assessed through laser aggregometry and laser diffractometry techniques. The findings revealed novel data of the correlation between whole blood viscosity and microrheological parameters of patients with ET. Overall, this study provides valuable preliminary evidence on the relationship between whole blood viscosity and microrheological parameters in the context of blood disorders.
Добавил в систему: Луговцов Андрей Егорович

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Interrelation of Blood Microrheological Parameters Measured by Optical Methods and Whole Blood Viscosity in Patients Suffering from Blood Disorders: a Pilot Studyстатья Исследовательская статья

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