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Hamet P.
Соавторы:
Орлов С.Н.
,
Tremblay J.
,
Акимова О.А.
,
Taurin S.
,
Кольцова С.В.
,
Лопина О.Д.
,
deBlois D.
,
Dulin N.
,
Haloui M.
,
Thorin-Trescases N.
,
PSHEZHETSKY A.
,
Pchejetski D.
,
Gagnon F.
показать полностью...
,
Котелевцев С.В.
,
Cowley A.W.
,
Dam T.V.
,
Gaudet D.
,
Gossard F.
,
Grygorczyk R.
,
Solban N.
,
Tremblay S.
,
Максимов Г.В.
,
Kotchen T.A.
,
Pausova Z.
,
Seda O.
,
Croisetiere C.
,
Gekle M.
,
Adarichev V.
,
Adragna N.
,
Bagrov A.Y.
,
Baskakov M.B.
,
Bennett M.R.
,
Bouchard G.
,
Champagne M.J.
,
Der Sarkissian S.
,
Devlin A.M.
,
El H.C.
,
Jompe M.
,
Kamernitskiǐ A.V.
,
Lavoie J.
,
Merlo E.
,
Pokudin N.I.
,
Richard L.
,
Tea B.S.
,
Teiger E.
,
Thorin E.
,
Герш Ю.А.
,
Гуо Д.
,
Рубцов А.М.
,
Шиян А.А.
,
Aksentsev S.L.
,
Allen B.G.
,
Antoniol G.
,
Beliveau R.
,
Bennett P.M.
,
Boulva F.
,
Bourcier N.
,
Broeckel U.
,
Brunelle P.
,
Burulina J.G.
,
Carlos E.H.
,
Deng A.
,
Deslauriers B.
,
Douglas J.G.
,
Dumas P.
,
Dutil J.
,
El_Hader C.
,
Farhat N.
,
Fortuno M.A.
,
Gaboury L.
,
Gindras D.
,
Grim C.E.
,
Grinchenko M.
,
Gurau A.
,
Gutkowska J.
,
Houde L.
,
Hudson T.J.
,
Jr
,
Kaldunski M.
,
Kirova R.
,
Kren V.
,
Kuznetsov S.R.
,
Labuda M.
,
Larochelle P.
,
Lauf P.
,
Lewanczuk R.
,
Li J.M.
,
Malekin S.
,
Malyshev I.
,
Maximova R.
,
Mongin A.A.
,
Moreau P.
,
Ono Y.
,
Pchezhetski D.
,
Petrovich M.
,
Pilote L.
,
Pintos J.
,
Platko J.
,
Rioux J.D.
,
Rodriquez X.
,
Ryazhsky G.G.
,
Schwartz J.H.
,
Schürch W.
,
Seyrantepe V.
,
Sun Y.R.
,
SunY
,
Thibault P.
,
Tonellato P.
,
Tremblay T.L.
,
Vezina H.
,
Анфиногенова Н.Д.
,
Гаврилова С.А.
,
Голубева А.В.
,
Капилевич Л.В.
,
Котелевцев Ю.В.
,
Кошелев В.Б.
,
Лунева О.Г.
,
Рубин А.Б.
,
Фадюкова О.Е.
95 статей
,
14 докладов на конференциях
,
1 тезисы доклада
,
1 патент
Количество цитирований статей в журналах по данным Web of Science: 1908, Scopus: 1820
IstinaResearcherID (IRID): 570317
Деятельность
Статьи в журналах
2015
Transcriptomic changes in Ca(2+)-depleted cells: Role of elevated intracellular [Na(+)]/[K(+)] ratio
Koltsova Svetlana V.
,
Tremblay Johanne
,
Hamet Pavel
,
Orlov Sergei N.
в журнале
Cell Calcium
, издательство
Churchill Livingstone
(United States)
, том 58, № 3, с. 317-324
DOI
2014
Transcriptomic changes triggered by hypoxia: evidence for HIF-1α -independent, [Na+]i/[K+]i-mediated, excitation-transcription coupling
Koltsova Svetlana V.
, Boris Shilov,
Burulina Julia G.
,
Akimova Olga A.
,
Mounsif Haloui
,
Kapilevich Leonid V.
, Gusakova Svetlana V.,
Johanne Tremblay
,
Pavel Hamet
,
Orlov Sergei N.
в журнале
PLoS ONE
, издательство
Public Library of Science
(United States)
DOI
2013
Cell volume and monovalent ion transporters: their role in triggering and progression of the celll death machinery
Orlov S.N.
,
Platonova A.A.
,
Hamet P.
,
Grygorczyk R.
в журнале
American Journal of Physiology - Cell Physiology
, издательство
American Physiological Society
(United States)
, том 305, с. 361-372
DOI
2013
Increased Renal Epithelial Na Channel Expression and Activity Correlate With Elevation of Blood Pressure in Spontaneously Hypertensive Rats
Haloui M.
,
Tremblay J.
,
Seda O.
,
Koltsova S.V.
,
Maksimov G.V.
,
Orlov S.N.
,
Hamet P.
в журнале
Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 62, № 4, с. 731-737
DOI
2013
Ubiquitous [Na+]i/[K+]i-sensitive transcriptome in mammalian cells: evidence for Ca2+i-independent excitation-transcription coupling
Koltsova S.V.
, Tryshina Y.,
Haloui M.
,
Akimova O.A.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
Global Medical Discovery (http://globalmedicaldiscovery.com)
2012
NKCC1 and hypertension: role in the regulation of vascular smooth muscle contractions and myogenic tone
Orlov S.N.
,
Koltsova S.V.
,
Tremblay J.
,
Baskakov M.B.
,
Hamet P.
в журнале
Annals of Medicine
, издательство
Taylor & Francis
(United Kingdom)
, том 44, № 1, с. 111-118
DOI
2012
Swelling rather than shrinkage precedes apoptosis in serum-deprived vascular smooth muscle cells
Platonova A.
,
Koltsova S.V.
,
Hamet P.
,
Grygorczyk R.
,
Orlov S.N.
в журнале
Apoptosis
, издательство
Springer Nature
(Switzerland)
, том 17, № 5, с. 429-438
DOI
2012
Ubiquitous [Na+]I/[K+]I-sensitive transcriptome mammalian cells: evidence for Ca2+I-independent excitation-transcription coupling
Koltsova S.V.
,
Trushina Y.A.
,
Haloui M.
,
Akimova O.A.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
PLoS ONE
, издательство
Public Library of Science
(United States)
2011
Long-term normalization of blood pressure in SHR and 1-kidney 1-clip rats by synthetic precursor of stable PAF analogue without systemic effects in normotensive rats
Malekin SI
,
Kotelevtsev SV
,
Gavrilova SA
,
Fadyukova OE
,
Golubeva AV
,
Grinchenko MI
,
Koshelev VB
,
Kotelevtsev YV
,
Hamet P.
,
Orlov SN
в журнале
Pathophysiology
, издательство
Elsevier BV
(Netherlands)
, том 18, № 2, с. 151-157
DOI
2011
Molecular origin of Na+/Li+ exchanger: evidence against the involvement of major cloned erythrocyte transporters
Koltsova S.V.
,
Trushina Y.A.
,
Akimova O.A.
,
Hamet P.
,
Orlov S.N.
в журнале
Pathophysiology
, издательство
Elsevier BV
(Netherlands)
, том 18, № 3, с. 207-213
2011
The search for a sensor of intracellular sodium involved in pathogenesis of hypertensive disease
Orlov S.N.
,
Hamet P.
в журнале
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
, издательство
Meditsina
(Russian Federation)
, том 7, с. 45-50
2010
Decreased NKCC1 activity in erythrocytes from African Americans with hypertension and dyslipidemia
Orlov S.N.
,
Gossard F.
,
Pausova Z.
,
Akimova O.A.
,
Tremblay J.
,
Grim C.E.
, Kotchen J.M., Kotchen T.A.,
Gaudet D.
,
Cowley A.W.
,
Hamet P.
в журнале
American Journal of Hypertension
, издательство
Elsevier BV
(Netherlands)
, том 23, № 3, с. 321-326
DOI
2010
Increased Na+/Li+ countertransport in erythrocytes of patients with essential hypertension is not caused by activation of Na+,Pi cotransport
Koltsova SV
,
Akimova OA
,
Kotelevtsev SV
,
Hamet P.
,
Orlov S.N.
в журнале
Артериальная гипертензия
, издательство
Общероссийская общественная организация "Содействия профилактике и лечению артериальной гипертензии "Антигипертензивная лига"
(Санкт-Петербург)
, том 16, с. 385-389
2010
Investigation of mechanism of p38 MAPK activation in renal epithelial cell from distal tubules triggered by cardiotonic steroids
Akimova O.A.
,
Lopina O.D.
,
Rubtsov A.M.
,
Hamet P.
,
Orlov S.N.
в журнале
Biochemistry (Moscow)
, издательство
Pleiades Publishing, Ltd
(Road Town, United Kingdom)
, том 75, № 8, с. 971-978
DOI
2010
Investigation of mechanism of p38 MAPK activation in renal epithelial cell from distal tubules triggered by cardiotonic steroids
Akimova O.A.,
Lopina O.D.
, Rubtsov A.M.,
Hamet P.
,
Orlov S.N.
в журнале
Biochemistry (Moscow)
, издательство
Pleiades Publishing, Ltd
(Road Town, United Kingdom)
, том 75, № 8, с. 971-978
2009
Death of ouabain-treated renal epithelial cells: evidence for p38 MAPK-mediated Na (i) (+) /K (i) (+) -independent signaling
Akimova Olga A.
,
Lopina Olga D.
, Rubtsov Alexander M.,
Gekle Michel
,
Tremblay Johanne
,
Hamet Pavel
,
Orlov Sergei N.
в журнале
Apoptosis
, издательство
Springer Nature
(Switzerland)
, том 14, № 11, с. 1266-1273
DOI
2009
Death of ouabain-treated renal epithelial cells: evidence for p38 MAPK-mediated Na (i) (+) /K (i) (+) -independent signaling
Akimova O.A.,
Lopina O.D.
,
Rubtsov A.M.
,
Gekle M.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
Apoptosis
, издательство
Springer Nature
(Switzerland)
, том 14, № 11, с. 1266-1273
2009
Excitation-contraction coupling in resistance mesenteric arteries: evidence for NKCC1-mediated pathway
Koltsova S.V.
,
Kotelevtsev S.V.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
Biochemical and Biophysical Research Communications
, издательство
Academic Press
(United States)
, том 379, № 4, с. 1080-1083
2009
HCO3-dependent impact of Na+,K+,2Cl- cotransport in vascular smooth muscle excitation-contraction coupling
Koltsova SV
,
Luneva OG
,
Lavoie JL
,
Tremblay J.
,
Maksimov GV
,
Hamet P.
,
Orlov SN
в журнале
Cellular Physiology and Biochemistry
, издательство
S. Karger AG
(Switzerland)
, том 23, № 4-6, с. 407-414
DOI
2009
Myogenic tone in mouse mesenteric arteries: evidence for P2Y receptor-mediated, Na(+), K (+), 2Cl (-) cotransport-dependent signaling
Koltsova S.V.
,
Maximov G.V.
,
Kotelevtsev S.V.
,
Lavoie J.L.
,
Tremblay J.
,
Grygorczyk R.
,
Hamet P.
,
Orlov S.N.
в журнале
Purinergic Signalling
, издательство
Springer Verlag
(Germany)
, том 5, № 3, с. 343-349
DOI
2008
Altered phosphorylation of RRXS*/T* motif in ouabain-treated renal epithelial cells is not mediated by inversion of the [Na+](i)/[K+](i) ratio
Akimova Olga A.
,
Lopina Olga D.
,
Tremblay Johanne
,
Hamet Pavel
,
Orlov Sergei N.
в журнале
Cellular Physiology and Biochemistry
, издательство
S. Karger AG
(Switzerland)
, том 21, № 4, с. 315-324
DOI
2008
Altered phosphorylation of RRXS*/T* motif in ouabain-treated renal epithelial cells is not mediated by inversion of the [Na](i)/[K+](i) ratio
Akimova O.A.
,
Lopina O.D.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
Cellular Physiology and Biochemistry
, издательство
S. Karger AG
(Switzerland)
, том 21, № 4, с. 315-324
2008
Na+]i/ [K+]i-independent death of ouabain-treated renal epithelial cells is not mediated by Na+,K+-ATPase internalization and de novo gene expression
Akimova O.A.
,
Hamet P.
,
Orlov S.N.
в журнале
European Journal of Physiology – Pflügers Archiv
, том 455, № 4, с. 711-719
2008
Systematic, genome-wide, sex-specific linkage of cardiovascular traits in french Canadians
Seda Ondrej
,
Tremblay Johanne
,
Gaudet Daniel
,
Brunelle Pierre-Luc
,
Gurau Alexandru
,
Merlo Ettore
,
Pilote Louise
,
Orlov Sergei N.
,
Boulva Francis
,
Petrovich Milan
,
Kotchen Theodore A.
,
Cowley Allen W.
,
Jr
,
Hamet Pavel
в журнале
Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 51, № 4, с. 1156-1162
DOI
2008
The death of ouabain-treated renal epithelial cells: evidence against anoikis occurrence
Akimova O.A.
, Poirier M.,
Kotelevtsev S.V.
,
Hamet P.
,
Orlov S.N.
в журнале
Apoptosis
, издательство
Springer Nature
(Switzerland)
, том 13, № 1, с. 670-680
2007
Death of ouabain-treated renal epithelial cells: Evidence for P38 MAPK-mediated [Na+](i)/[K+](i)-independent signaling
Akimova O.
, Koltsova S.,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
Canadian Journal of Cardiology
, издательство
Pulsus Group Inc.
(Canada)
, том 23, с. 42C-42C
2007
Independent death of renal epithelial cells triggered by cardiotonic steroids is not mediated by NA(+),K+-atpase internalization and de Novo gene expression
Akimova O.
,
Hamet P.
,
Orlov S.N.
в журнале
Canadian Journal of Cardiology
, издательство
Pulsus Group Inc.
(Canada)
, том 23, с. 97C-97C
2007
Na]i -induced c-Fos expression is not mediated by activation of the 5' -promoter containing known transcriptional elements
Haloui M.
,
Taurin S.
,
Akimova OA
, Guo DF,
Tremblay J.
,
Dulin NO
,
Hamet P.
,
Orlov SN
в журнале
FEBS Journal
, издательство
Blackwell Publishing Inc.
(United Kingdom)
, том 274, № 14, с. 3557-67
2007
Proteomic-based identification of upstream intermediates of Na plus i,K plus i-independent death signaling triggered by interaction of cardiotonic steroids with alpha-subunit of Na,K-ATPase
Akimova Olga A.
,
Hamet Pavel
,
Orlov Sergei N.
в журнале
FASEB Journal
, издательство
Federation of American Societies for Experimental Biology
(United States)
, том 21, № 5, с. A534-A534
2006
Age-dependent development of hypertension in SHR: Role of augmented ENaC expression
Haloui Mounsif
,
Tremblay Johanne
,
Sun Yu-Lin
,
Seda Ondrej
,
Orlov Sergei N.
,
Hamet Pavel
в журнале
Journal of Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 24, с. 133-133
2006
HCaRG interaction with actin and ion transporters promotes renal cell migration
Carlos El Hader
,
Solban Nicolas
,
Croisetiere Christian
,
Tremblay Sandra
,
Devlin Alison M.
,
Orlov Sergei N.
,
Hamet Pavel
,
Tremblay Johanne
в журнале
Journal of Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 24, с. 94-94
2006
Intracellular monovalent ions as second messengers
Orlov S.N.
,
Hamet P.
в журнале
Journal of Membrane Biology
, издательство
Springer Verlag
(Germany)
, том 210, № 3, с. 161-172
DOI
2006
Modest intracellular acidification suppresses death signaling in ouabain-treated cells
Akimova O.A.
,
Pchejetski D.
,
Hamet P.
,
Orlov S.N.
в журнале
Pflugers Archiv European Journal of Physiology
, издательство
Springer Verlag
(Germany)
, том 451, № 4, с. 569-578
DOI
2006
Proteomics-based identification of intermediates of [Na+]i/[K+]i-independent signaling triggered by cardiotonic steroids (CTS)
Akimova O.A.
,
Hamet P.
,
Orlov S.N.
в журнале
Journal of Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 24, с. S349-S349
2006
Renal repair and regeneration: Study of a candidate gene HCaRG
El Hader C.
,
Tremblay S.
,
Bourcier N.
,
Croisetiere C.
,
Solban N.
,
Orlov S.N.
,
Hamet P.
,
Tremblay J.
в журнале
Journal of Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 24, с. S147-S147
2006
Search for intracellular Na+ sensor: Lack of the involvement of 5 '-UTR in Na+I-induced c-Fos expression
Haloui M.
,
Taurin S.
,
Guo D.F.
,
Tremblay J.
,
Dulin N.O.
,
Hamet P.
,
Orlov S.N.
в журнале
Journal of Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 24, с. S158-S158
2006
The death of cardiotonic steroid-treated cells: evidence of Na-i(+),K-i(+)-independent H-i(+)-sensitive signalling
Orlov S.N.
,
Hamet P.
в журнале
Acta Physiologica
, издательство
Blackwell Publishing Inc.
(United Kingdom)
, том 187, № 1-2, с. 231-240
DOI
2006
The rapid decline of MTT reduction is not a marker of death signaling in ouabain-treated cells
Akimova O.A.
,
Mongin A.A.
,
Hamet P.
,
Orlov S.N.
в журнале
Cellular and Molecular Biology
, издательство
C M B Association
(France)
, том 52, № 8, с. 68-74
2006
[Na+]i-induced c-fos expression is not mediated by activation of 5 '-promoter containing all known transcriptional elements
Haloui Mounsif
,
Taurin Sebastien
,
Guo Deng-Fu
,
Tremblay Johanne
,
Dulin Nickolai O.
,
Hamet Pavel
,
Orlov Sergei N.
в журнале
Journal of Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 24, с. 238-238
2005
Cardiotonic steroids differentially affect intracellular Na+ and [Na+](i)/[K+](i)-independent signaling in C7-MDCK cells
Akimova O.A.
,
Bagrov A.Y.
,
Lopina O.D.
,
Kamernitsky A.V.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
Journal of Biological Chemistry
, издательство
American Society for Biochemistry and Molecular Biology Inc.
(United States)
, том 280, № 1, с. 832-839
DOI
2005
Cardiotonic steroids differentially affect intracellular Na+ and [Na+]i/[K+]i-independent signaling in C7-MDCK cells
Akimova O.A.
,
Bagrov A.Y.
,
Lopina O.D.
,
Kamernitsky A.V.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
в журнале
Journal of Biological Chemistry
, издательство
American Society for Biochemistry and Molecular Biology Inc.
(United States)
, том 280, № 1, с. 832-839
2005
Cardiotonic steroids: novel mechanisms of Na+i-mediated and –independent signaling involved in the regulation of gene expression, proliferation and cell death
Orlov S.N.
,
Akimova O.A.
,
Hamet P.
в журнале
Current Hypertension Reviews
, издательство
Bentham Science Publishers
(Netherlands)
, том 1, с. 243-257
2005
HCaRG increases renal cell migration by a TGF-a autocrine loop mechanism
El_Hader C.
,
Tremblay S.
,
Solban N.
,
Gindras D.
,
Beliveau R.
,
Orlov S.N.
,
Hamet P.
,
Tremblay J.
в журнале
American Journal of Physiology - Renal Physiology
, издательство
American Physiological Society
(United States)
, том 289, с. F1273-F1280
2005
Quantitative founder effect analysis of French-Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension. Am.J.Hum.Genet
Hamet P.
,
Merlo E.
,
Seda O.
,
Broeckel U.
,
Tremblay J.
,
Kaldunski M.
,
Gaudet D.
,
Bouchard G.
,
Deslauriers B.
,
Gagnon F.
,
Antoniol G.
,
Pausova Z.
,
Labuda M.
,
Jompe M.
,
Gossard F.
,
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Tonellato P.
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Orlov S.N.
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Pintos J.
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Platko J.
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Hudson T.J.
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Rioux J.D.
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Kotchen T.A.
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в журнале
American Journal of Human Genetics
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University of Chicago Press
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, том 76, с. 815-832
2005
Search for intermediates of Na+,K+-ATPase-mediated [Na+](i)/[K+](i)-independent death signaling triggered by cardiotonic steroids
Akimova O.A.
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Hamet P.
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Orlov S.N.
в журнале
Journal of General Physiology
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Rockefeller University Press
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, том 126, № 1, с. 66A-67A
2005
Search for intermediates of Na+,K+-ATPase-mediated [Na+]i/[K+]i-independent death signaling triggered by cardiotonic steroids
Akimova O.A.
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Lopina O.D.
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Hamet P.
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Orlov S.N.
в журнале
Pathophysiology
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Elsevier BV
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, том 12, № 2, с. 125-135
2004
Apoptosis in serum-deprived vascular smooth muscle cells: evidence for cell volume-independent mechanism
Orlov S.N.
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Pchezhetski D.
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Taurin S.
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Thorin-Trescases N.
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Maximov G.V.
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Pshezhetsky A.V.
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Rubin A.B.
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Hamet P.
в журнале
Apoptosis
, издательство
Springer Nature
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, том 9, с. 55-66
2004
Na+/K+ pump end endothelial cell survival: [Na+]i/[K+]i-imdependent necrosis triggered by ouabain, and protection against apoptosis triggered by elevation of [Na+]i
Orlov S.N.
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Thorin-Trescases N.
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Pchejetski D.
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Taurin S.
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Farhat N.
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Tremblay J.
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Thorin E.
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Hamet P.
в журнале
Eur.J.Physiol. - Pflugers Archiv
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2003
HCaRG is a novel regulator of renal epithelial cell growth and differentiation causing G2M arrest
Devlin A.M.
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Solban N.
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Tremblay S.
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Gutkowska J.
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Schürch W.
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Orlov S.N.
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Lewanczuk R.
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Hamet P.
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Tremblay J.
в журнале
American Journal of Physiology - Renal Physiology
, издательство
American Physiological Society
(United States)
, том 284, с. F753-F762
2003
Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+](i)/[K+](i) ratio
Pchejetski D.
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Taurin S.
, Sarkissian S.D.,
Lopina O.D.
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Pshezhetsky A.V.
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Tremblay J.
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deBlois D.
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Hamet P.
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Orlov S.N.
в журнале
Biochemical and Biophysical Research Communications
, издательство
Academic Press
(United States)
, том 301, № 3, с. 735-744
DOI
2003
Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+]i/[K+]i ratio
Pchejetski D.
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Taurin S.
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Der Sarkissian S.
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Lopina O.D.
,
Pshezhetsky A.V.
,
Tremblay J.
,
deBlois D.
,
Hamet P.
,
Orlov S.N.
в журнале
Biochemical and Biophysical Research Communications
, издательство
Academic Press
(United States)
, том 301, № 3, с. 735-744
2003
Na/K pump and intracellular monovalent cations: novel mechanism of excitation-transcritpion coupling involved in inhibition of apoptosis (invited review
Taurin S.
,
Hamet P.
,
Orlov S.N.
в журнале
Molecular Biology
, издательство
Maik Nauka/Interperiodica Publishing
(Russian Federation)
, том 37, с. 371-381
2003
[3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein
Orlov S.N.
,
Pchejetski D.V.
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Der_Sarkissian S.
,
Adarichev V.
,
Taurin S.
,
Pshezhetsky A.V.
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Tremblay J.
,
Maximov G.V.
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deBlois D.
,
Bennett M.R.
,
Hamet P.
в журнале
Apoptosis
, издательство
Springer Nature
(Switzerland)
, том 8, с. 199-208
2002
Proteome analysis and functional expression identify mortalin as an anti-apoptotic gene induced by elevation of [Na+]i/[K+]i ratio in cultured vascular smooth muscle cells
Taurin S.
,
Seyrantepe V.
,
Orlov S.N.
,
Tremblay T.L.
,
Thibault P.
,
Bennett M.R.
,
Hamet P.
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Pshezhetsky A.V.
в журнале
Circulation Research
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Lippincott Williams & Wilkins Ltd.
(United States)
, том 91, с. 915-922
2002
Suppression of programmed cell death by intracellular cAMP is not mediated by exprsession of genes encoding an inhibitor of apoptosis
Taurin S.
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Ryazhsky G.G.
,
Maximova N.V.
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Hamet P.
,
Pshezhetsky A.V.
,
Orlov S.N.
в журнале
Biochemistry (Moscow)
, издательство
Pleiades Publishing, Ltd
(Road Town, United Kingdom)
, том 67, с. 254-259
2002
c-Fos expression in vascular smooth muscle cells: evidence for intracellular-sodium-mediated, calcium-independent mechanism
Taurin S.
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Grygorczyk R.
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Tremblay J.
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Hamet P.
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Orlov S.N.
в журнале
JOURNAL OF PHYSIOLOGY-LONDON
, том 543, с. 835-847
2001
Antiproliferative effect of brief exporsure to cholera toxin in vascular smooth muscle cells: role of cAMP and protein kinase A
Thorin-Trescases N.
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Orlov S.N.
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Taurin S.
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Dulin N.O.
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Allen B.G.
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deBlois D.
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Tremblay J.
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Pshezhetsky A.V.
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Hamet P.
в журнале
Canadian Journal of Physiology and Pharmacology
, издательство
NRC Research Press
(Canada)
, том 79, с. 471-480
2001
Apoptosis in cardiovascular remodeling – effect of medication (invited review)
deBlois D.
,
Orlov S.N.
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Hamet P.
в журнале
Cardiovascular Drugs and Therapy
, издательство
Springer Nature
(Switzerland)
, том 15, с. 539-545
2001
Inhibition of Na+,K+ pump affects nucleic acid synthesis and smooth muscle cell proliferation via elevation of [Na+]i/[K+]i ratio: possible implication in vascular remodeling
Orlov S.N.
,
Taurin S.
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Tremblay J.
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Hamet P.
в журнале
Journal of Clinical Hypertension
, издательство
Le Jacq Communications, Inc.
(United States)
, том 19, с. 1559-1565
2001
Replacement of 1-Na-K-ATPAse of Dahl rats by Milan rats lowers blood pressure but does not affect its activity
Orlov S.N.
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Dutil J.
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Hamet P.
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Deng A.
в журнале
Physiological Genomics
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American Physiological Society
(United States)
, том 7, с. 171-177
2001
Swelling-induced K+ fluxes in vascular smooth muscle cells are mediated by charybdotoxin-sensitve K+ channels
Anfinogenova Y.J.
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Adragna N.
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Lauf P.
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Hamet P.
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в журнале
Cellular Physiology and Biochemistry
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S. Karger AG
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, том 11, с. 295-310
2000
Dual effect of adenosine on vascular smooth muscle [3H]-thymidine DNA labelling: receptor-mediated modulation of DNA synthesis and inhibition of thymidine uptake
Thorin-Trescases N.
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Ono Y.
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Tremblay J.
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Hamet P.
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Orlov S.N.
в журнале
Journal of Vascular Research
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S. Karger AG
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, том 37, с. 477-484
2000
Inversion of the intracellular Na+/K+ ratio blocks apoptosis in vascular smooth muscle cells via induction of RNA synthesis
ORLOV S.N.
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Taurin S.
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Thorin-Trescases N.
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Dulin N.O.
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Tremblay J.
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Hamet P.
в журнале
Hypertension
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Lippincott Williams & Wilkins Ltd.
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, том 35, с. 1062-1068
1999
ATP-induced inhibition of Na+,K+, Cl- cotransport in Madin-Darby canine kidney cells: lack of the involvement of known purinoceptor-coupled signaling pathways
Gagnon F.
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Dulin N.O.
,
Tremblay J.
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Hamet P.
,
Orlov S.N.
в журнале
Journal of Membrane Biology
, издательство
Springer Verlag
(Germany)
, том 167, с. 193-204
1999
Activation of cAMP signaling transiently inhibits apoptosis in vascular smooth muscle cells in a site upstream caspase-3
Orlov S.N.
,
Thorin-Trescases N.
,
Dulin N.O.
,
Dam T.V.
,
Fortuno M.A.
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Tremblay J.
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Hamet P.
в журнале
Cell Death and Differentiation
, издательство
Nature Publishing Group
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, том 6, с. 661-672
1999
Apoptosis in hypertension: mechanisms and implications in vascular remodeling (invited review
Orlov S.N.
,
de_Blois D.
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Tremblay J.
,
Hamet P.
в журнале
Cardioovasc. Risk Factors
, том 9, № 2, с. 67-79
1999
Genetic and biochemical determinants of abnormal ion transport in primary hypertension (invited review
Orlov S.N.
,
Adragna N.
,
Adarichev V.A.
,
Hamet P.
в журнале
American Journal of Physiology - Cell Physiology
, издательство
American Physiological Society
(United States)
, том 276, с. C511-C536
1999
Heat stress preconditioning does not protect renal apithelial Na+,K+,Cl- and Na+,Pi cotransporters from their modulation by severe heat stress
Gagnon F.
,
Orlov S.N.
,
Chanpagne M.J.
,
Tremblay J.
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Hamet P.
в журнале
Biochimica et biophysica acta
, издательство
Elsevier Pub. Co.
(Amsterdam, Netherlands)
, том 1421, с. 163-174
1999
Inversion of the intracellular Na+/K+ ratio blocks apoptosis in vascular smooth muscle at a site upstream of caspase-3
Orlov S.N.
,
Thorin-Trescases N.
,
Kotelevtsev S.V.
,
Tremblay J.
,
Hamet P.
в журнале
Journal of Biological Chemistry
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American Society for Biochemistry and Molecular Biology Inc.
(United States)
, том 274, с. 16545-16552
1999
Na+,K+ pump and Na+-coupled ion carriers in isolated mammalian kidney epithelial cells: regulation by protein kinase C (invited review)
Gagnon F.
,
Hamet P.
,
Orlov S.N.
в журнале
Canadian Journal of Physiology and Pharmacology
, издательство
NRC Research Press
(Canada)
, том 77, с. 305-319
1999
Protection against necrosis but not apoptosis by heat-stress proteins in vascular smooth muscle cells: evidence for distinct modes of cell death
Champagne M.J.
,
Dumas P.
,
Orlov S.N.
,
Bennett M.
,
Hamet P.
,
Tremblay J.
в журнале
Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 33, с. 906-913
1999
Purinergic modulation of Na+,K+,Cl- cotransport and MAP kinases is limited to C11-MDCK cells resembling intercalated cells from collecting ducts
Orlov S.N.
,
Dulin N.O.
,
Gagnon F.
,
Gekle M.
,
Douglas J.G.
,
Schwartz J.H.
,
Hamet P.
в журнале
Journal of Membrane Biology
, издательство
Springer Verlag
(Germany)
, том 172, с. 225-234
1999
Sibling resemblance of erythrocyte ion transporters in French-Canadian sibling-pairs affected with essential hypertension
Orlov S.N.
,
Pausova Z.
,
Gossard F.
,
Gaudet D.
,
Tremblay J.
,
Kotchen T.
,
Cowley A.
,
Larochelle P.
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Hamet P.
в журнале
Journal of Clinical Hypertension
, издательство
Le Jacq Communications, Inc.
(United States)
, том 17, с. 1859-1865
1998
Can we use erythrocytes for the study of the activity of ubiquitous Na+-H+ exchanger (NHE1) in essential hypertension?
Orlov S.N.
,
Kuznetsov S.R.
,
Pokudin N.I.
,
Tremblay J.
,
Hamet P.
в журнале
American Journal of Hypertension
, издательство
Elsevier BV
(Netherlands)
, том 11, с. 774-783
1998
Complete inhibition of Na+,K+,Cl- cotransport in Madin-Darby canine kidney cells by PMA-sensitive protein kinase C
Gagnon F.
,
Orlov S.N.
,
Tremblay J.
,
Hamet P.
в журнале
Biochimica et biophysica acta
, издательство
Elsevier Pub. Co.
(Amsterdam, Netherlands)
, том 1369, с. 233-239
1998
Na+-H+ exchange in vascular smooth musccle cells is controlled by GTP-bindig proteins
Orlov S.N.
,
Aksentsev S.L.
,
Pokudin N.I.
,
Tremblay J.
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Hamet P.
в журнале
Hypertension
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Lippincott Williams & Wilkins Ltd.
(United States)
, том 31, с. 259-265
1996
Apoptosis and vascular wall remodelling in hypertension (invited review). Can.J.Physiol.Pharmacol
Hamet P.
,
deBlois D.
,
Dam T.V.
,
Richard L.
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Teiger E.
,
Tea B.S.
,
Orlov S.N.
,
Tremblay J.
в журнале
Canadian Journal of Physiology and Pharmacology
, издательство
NRC Research Press
(Canada)
, том 74, с. 850-861
1996
Apoptosis in vascular smooth muscle cells: role of cell shrinkage
Orlov S.N.
,
Dam T.V.
,
Tremblay J.
,
Hamet P.
в журнале
Biochemical and Biophysical Research Communications
, издательство
Academic Press
(United States)
, том 221, с. 708-715
1996
Bumetanide-sensitive ion flixes in vascular smooth muscle cells: lack of functional Na+,K+,2Cl- cotransport
Orlov S.N.
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Tremblay J.
,
Hamet P.
в журнале
Journal of Membrane Biology
, издательство
Springer Verlag
(Germany)
, том 153, с. 125-135
1996
Cell volume in vascular smooth muscle cells is regulated by bumetanide-sensitive ion transport
ORLOV S.N.
,
Tremblay J.
,
Hamet P.
в журнале
American Journal of Physiology - Cell Physiology
, издательство
American Physiological Society
(United States)
, том 270, с. C1388-C1397
1996
The time window of apoptosis: a new component in the therapeutic strategy for cardiovascular remodeling
Hamet P.
,
Moreau P.
,
Dam T.V.
,
Orlov S.N.
,
Tea B.S.
,
de_Blois D.
,
Tremblay J.
в журнале
Journal of Clinical Hypertension
, издательство
Le Jacq Communications, Inc.
(United States)
, том 14, № suppl 5, с. S65-S70
1996
cAMP signaling inhibits dihydropyridine-sensitive Ca2+ influx in vascular smooth muscle cells
Orlov S.N.
,
Tremblay J.
,
Hamet P.
в журнале
Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 27, с. 774-780
1995
Alteration of membrane transport of monovalent ions in primary hypertension: what do we know about it after 20 years? (invited review)
Orlov S.N.
,
Tremblay J.
,
Hamet P.
в журнале
Кардиология
, издательство
Общероссийская общественная организация Общество специалистов по сердечной недостаточности
(Москва)
, том 35, № 10, с. 14-21
1995
Altered -adrenergic regulation of Na-K-Cl cotransport in cultured smooth muscle cells from the aorta of spontaneously hypertensive rats
Orlov S.N.
,
Tremblay J.
,
Hamet P.
в журнале
American Journal of Hypertension
, издательство
Elsevier BV
(Netherlands)
, том 8, с. 739-747
1995
Apoptosis in target organs of hypertension. Hypertension
Hamet P.
,
Richard L.
,
Dam T.V.
,
Teiger E.
,
Orlov S.N.
,
Gaboury L.
,
Gossard F.
,
Tremblay J.
в журнале
Hypertension
, издательство
Lippincott Williams & Wilkins Ltd.
(United States)
, том 26, с. 642-648
Статьи в сборниках
2008
Hypertension-related, calcium regulated gene, HCaRG, increases cell migration by binding actin monomers and inhibiting their polymerisation
Tremblay J.
,
Croisetiere C.
,
El Hader C.
,
Solban N.
,
Tremblay S.
,
Orlov S.N.
,
Hamet P.
в сборнике
18th Scientific Meeting of the European-Society-of-Hypertension/22nd Scientific Meeting of the International-Society-of-Hypertension
, серия
Journal of Hypertension
, место издания
Lippincott Williams & Wilkins Ltd United States
, том 26, с. S431-S431
2005
Na+/K+ pump as endothelial cell death receptor triggered by ouabain
Orlov S.N.
,
Thorin-Trescases N.
,
Pchejetski D.
,
Akimova O.
,
Taurin S.
,
Tremblay J.
,
Thorin E.
,
Hamet P.
в сборнике
In: Second messengers and phosphoprotein signaling. Procceding of the 12th International Conference on Second Messegers and Phosphoproteins , M. Tremblay and A.K. Shrivastava eds
, место издания
MEDIMOND International Proceeding M.D. Anand-Srivastava
, с. 153-157
2004
Angiotensin as a cytokine implicated in accelerated cellular turnover
Hamet P.
,
ORLOV S.N.
,
deBlois D.
,
SunY
,
Kren V.
,
Tremblay J.
в сборнике
Handbook of Experimental Pharmacology – Angiotensin, T. Unger and B.A. Schölkens eds
, место издания
Springer Verlag Publ
, том 163, с. 71-98
2004
Apoptosis vs oncosis: role of cell volume and intracellular monovalent cations
Orlov SN
,
Hamet P.
в сборнике
Advances in Experimental Medicine and Biology, Cell Volume and Signaling, P. Lauf and N. Adragna eds
, место издания
Springer Science and Business Media Inc
, том 559, с. 219-233
2002
A genealogical study of essential hypertension with and without obesity in French
Pausova Z.
,
Jompe M.
,
Houde L.
,
Vezina H.
,
Orlov S.N.
,
Gossard F.
,
Gaudet D.
,
Tremblay J.
,
Kotchen T.A.
,
Cowley A.W.
,
Bouchard G.
,
Hamet P.
в сборнике
Canadians Obesity Research
, том 10, с. 463-470
2002
Genetics of programmed cell death and proliferation (invited review)
Orlov S.N.
,
Tremblay J.
,
deBlois D.
,
Hamet P.
в сборнике
Seminars in Nephrology
, том 22, с. 161-171
2002
The 1-Na/K pump does not mediate the involvement of ouabain in the development of hypertension in rats
Orlov S.N.
,
Taurin S.
,
Hamet P.
в сборнике
Blood Pressure
, том 11, с. 56-62
1999
Hypertensoin as a cardiovascular proliferative disorder (invited review
DeBlois D.
,
Orlov S.N.
,
Hamet P.
в сборнике
In: Apoptosis in cardiac biology H.Shumkert and GAJ Riegger eds
, место издания
Kluwer Academic Publ Boston-Doredrecht-London
, с. 213-222
1995
Genes of intracellular calcium metabolism and blood pressure control in primary hypertension (invited review)
Orlov S.N.
,
Li J.M.
,
Tremblay J.
,
Hamet P.
в сборнике
Seminar in Nephrology
, том 15, с. 569-592
1995
Intracellular signalling mechanisms in hypertension (invited review)
Hamet P.
,
Orlov S.N.
,
Tremblay J.
в сборнике
Hypertension: Physiology, Diagnosis and Treatment, Second Edition. Ed.by J.H. Laragh and B.M. Brenner
, место издания
Brenner, Raven Press, Ltd New York
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Доклады на конференциях
2013
Both cell volume changes and Na+i/K+i-sensitive transcriptome contribute to inflammatory and immune system responses
Авторы:
Koltsova S.V.
,
Baskakov M.B.
,
Malyshev I.Yu
,
Hamet P.
,
Orlov S.N.
10th International Congress «Cell Volume Regulation: Novel Therapeutic Targets & Pharmacological Approaches»
, Russia, Moscow, Россия, 26-29 августа 2013
2013
ENaC expression and activity correlate with development of hypertension in spontaneously hypertensive rats
(Устный)
Авторы:
Haloui M.
,
Tremblay J.
,
Seda O.
,
Koltsova SV
,
Maksimov GV
,
ORLOV SN
,
Hamet P.
10th International Congress «Cell Volume Regulation: Novel Therapeutic Targets & Pharmacological Approaches»
, Russia, Moscow, Россия, 26-29 августа 2013
2013
Transcriptomic changes in Ca2+-depleted cells: a major role of elevated intracellular [Na+]i/[K+]i ratio
Авторы:
Koltsova S.V.
,
Kotelevtsev S.V.
,
Tremblay J.
,
Hamet P.
,
Orlov S.N.
10th International Congress «Cell Volume Regulation: Novel Therapeutic Targets & Pharmacological Approaches»
, Russia, Moscow, Россия, 26-29 августа 2013
2012
Augmented renal ENaC expression and activity correlate with age-dependent development of hypertension in female spontaneously hypertensive rats (SHR)
(Устный)
Авторы:
Haloui M.
,
Tremblay J.
,
Seda O.
,
Koltsova SV
,
Maksimov GV
,
ORLOV SN
,
Hamet P.
24th Meeting of the International Society of Hypertension. The Future of Cardiovascular Protection.
, Австралия, 30 сентября - 4 октября 2012
2012
Identification of ubiquitous [Na+]i/[K+]i-sensitive transcriptome: evidence for Ca2+i-independent excitation-transcription coupling.
Авторы:
Orlov SN
,
Koltsova SV
,
Trushina Y.
,
Haloui M.
,
Akimova OA
,
Tremblay J.
,
Hamet P.
24th Meeting of the International Society of Hypertension. The Future of Cardiovascular Protection.
, Австралия, 30 сентября - 4 октября 2012
2012
Identification of ubiquitous [Na+]i/[K+]i-sensitive transcriptome: evidence for Ca2+i-independent excitation-transcription coupling.
Авторы:
Koltsova SV
,
Haloui M.
,
Akimova OA
,
Tremblay J.
,
Hamet P.
,
Orlov SN
,
Trushina Y.
The 2nd ISH New Investigators` Symposium
, Австралия, 29 сентября 2012
2012
Na,K-ATPase and cardiotonic steroids: identification of [Na+]i/[K+]i-independent death signaling.
Авторы:
Akimova OA
,
Koltsova SV
,
Trushina YA
,
Hamet P.
,
Orlov SN
3rd International Workshop on Expression, Structure and Function of Membrane Proteins.
, Италия, 23-27 сентября 2012
2012
Molecular origin of Na+/Li+ exchanger: Evidence against the involvement of major cloned erythrocyte transporters.
Авторы:
Trushina YA
,
Koltsova SV
,
Akimova OA
,
Hamet P.
,
Orlov SN
12th Annual McGill Biomedical Graduate Conference.
, Канада, 16 февраля 2012
2012
Swelling rather than shrinkage precedes apoptosis in serum-deprived vascular smooth muscle cells.
Авторы:
Platonova A.
,
Koltsova SV
,
Hamet P.
,
Grygorczyk R.
,
Orlov SN
12th Annual McGill Biomedical Graduate Conference.
, Канада, 16 февраля 2012
2011
Swelling rather than shrinkage precedes apoptosis in serum-deprived vascular smooth muscle cells
(Устный)
Авторы:
Platonova A.
,
Koltsova SV
,
Hamet P.
,
Grygorczyk R.
,
ORLOV SN
14e Congrés annuel des étudiants, stagiaires et résidents du Centre de recherche du CHUM
, Montréal, Канада, 13 декабря 2011
2011
CTS-induced p38 MAPK-mediated signaling
(Устный)
Авторы:
Akimova OA
,
ORLOV SN
,
Hamet P.
Interactions of cardiac steroids and the Na+,K+-ATPase: molecular, physiological and pharmacological implications
, Jerusalem, Израиль, 28 февраля - 2 марта 2011
2010
Molecular origin of Na+/Li+ countertransport: evidence against Na+-coupled Pi cotransporter.
Авторы:
Koltsova SV
,
Akimova OA
,
Tremblay J.
,
Kotelevtsev SV
,
Hamet P.
,
Orlov SN
The 23rd scientific meeting of the international society of hypertension.
, Канада, 26-30 сентября 2010
2010
Myogenic tone in mesenteric arteries involves P2Y receptor-mediated, NKCC1-dependent signaling.
Авторы:
Koltsova SV
,
Maximov GV
,
Lavoie JL
,
Kotelevtsev SV
,
Tremblay J.
,
Grygorczyk R.
,
Hamet P.
,
Orlov SN
The 23rd scientific meeting of the international society of hypertension.
, Канада, 26-30 сентября 2010
2010
Myogenic tone in mesenteric arteries involves P2Y receptor-mediated, NKCC1-dependent signaling.
Авторы:
Koltsova SV
,
Maximov GV
,
Lavoie JL
,
Kotelevtsev SV
,
Tremblay J.
,
Grygorczyk R.
,
Hamet P.
,
Orlov SN
6th International Congress of Pathophysiology
, Канада, 22-25 сентября 2010
Тезисы докладов
2013
Both cell volume changes and Na+i/K+i sensitive transcriptome contribute to inflammatory and immune system responses
Koltsova S.V.
,
Baskakov M.B.
,
Malyshev I.Yu
,
Hamet P.
,
Orlov S.N.
в сборнике
Бюллетень сибирской медицины
, том 12, тезисы, с. 43-43
Патенты
2004
New uses of ouabain and ouabain-like molecules in apoptosis related pathologies U.S. patent
Авторы:
Orlov S.N.
,
Hamet P.
,
Tremblay J.
#6,699,676 B1 , 2 марта